II group. Drugs whose use in the first 3.10 weeks of pregnancy in most cases, can cause destruction of the embryo and / or miscarriage:

antipsychotics (chlorpromazine, neuleptil, DITT, etc.)

preparations Li (carbonate and hydroxybutyrate Li)

antiparkensonicheskie having a central M-holinoblokiruyuschim action (bellazon, dinezin, norakin, tropatsin, tsiklodol, etc.)

anticonvulsants (difenina, carbamazepine)

NSAIDs (meloxicam, naproxen, piroxicam, phenylbutazone, etc.)

anticoagulants direct action (neodikumarina) sinkumar etc.

antidiabetic drugs for oral use (bucarban, glikvidon, izodibut etc.)

glucocorticosteroids (cortisone, prednisolone, triamcinolone, dexamethasone, methylprednisolone, fludrokortizon, etc.)

drugs to treat diseases of the thyroid gland (iodide, tiamazol)

antibiotics (aminoglycosides, tetracyclines, rifampitsillin)

antimalarial drugs (Plaquenil, hingaminom, quinine, etc.)

alkogolsoderzhaschie dosage forms

III group. Medicines moderate risk:

tricyclic antidepressants (amitriptyline, imipramine, etc.)

tranquilizers - carbamic esters propanediol (meprobamate)

antiparkensonicheskie drugs - derivatives levopy

medications containing female sex hormones - estrogens

sulfonamides

drugs for the treatment of protozoal infections - metronidazole.

Thus we can conclude that the prescription drugs to pregnant women should consider not only their direct effects on the fetus, but the features of the pharmacokinetics of drugs in the body pregnant women, as well as the state of the placenta, which depends on its barrier function.